DOWNEY — Two weeks after her disappearance, police and family members are desperately asking for any information to help bring Regan “Reina” Koeppe home.

Koeppe, age 25 with diminished mental capacity, was reported missing on the morning of Dec. 7. She was wearing unknown type clothing, blue Reebok shoes and was possibly carrying a black backpack, according to the Downey Police Department.

Koeppe suffers from several conditions that require medication, without which she is susceptible to seizures.

On Tuesday, law enforcement officials, joined by Koeppe’s family, held a press conference outside Downey Police Station.

“It’s important that we get her photo out there,” said Police Chief Leslie Murray. “Our main concern right now is finding her and bringing her home safely to her family.”

Murray said detectives have followed up on all leads and collaborated with other agencies, including Los Angeles County Sheriff’s Department, the Attorney General’s office, homeless outreach and the Department of Mental Health.

Police were able to secure Ring camera footage of a woman walking about two blocks from Koeppe’s home around 3 am the morning before her disappearance. It is believed but not confirmed to be Koeppe.

Leads have so far come up empty.

“We’re really reaching out to get the information out to a larger community,” said Murray. “Here in Downey, it’s been on our radar for the last two weeks…but we’re hoping to reach the greater Southern California area to spark some more leads for us.”

DPD says that nothing – including abduction – is off the table.

Mom Rochelle Koeppe described her daughter as “resilient and full of joy…but also naïve.”

“She is very easily exploitable. Anybody who knows her loves her…but she is the type that will walk up to a stranger and go off with them,” she said. “She has no sense of danger.”

Rochelle said have been no other incidents of Koepee running away, adding that she is kept under constant supervision.

She pleaded with those who may have Koepee to “please return her.”

“She is an essential part of our family. She is the joy of our family,” she said. “Our family is revolved around her, and we need her back.”

Brother Daniel described Koepee as “his best friend.”

“All I want for Christmas is my sister home,” he said.

Anyone with information is encouraged to call (562) 904-2308.